Microdosing Protocols and How to Create Your Own

Microdosing is often described as a practice built on intention rather than intensity. Instead of dramatic shifts, it focuses on subtle adjustments in mood, focus, and perception that unfold gradually through daily life. These outcomes are shaped not only by the substance itself, but by how often it is used, when it is taken, and how much rest is built into the process.

To bring structure and safety to this approach, many people follow established microdosing protocols. These frameworks are designed to reduce tolerance, encourage reflection, and help users observe patterns over time. While no single method works for everyone, understanding the most common protocols makes it easier to choose or adapt an approach that fits your goals.

What microdosing protocols are

A microdosing protocol is a structured schedule that outlines when to take a low dose of magic mushrooms and when to pause. These schedules emphasize consistency and rest, helping prevent tolerance buildup while allowing time to observe subtle effects.

Most protocols run for four to eight weeks and are followed by a break lasting two to four weeks. This reset period is considered essential, as psilocybin can lose effectiveness when taken too frequently. Committing to a full cycle provides clearer insight into whether a protocol is supportive or not.

The Fadiman protocol

The Fadiman protocol is one of the most widely recognized microdosing frameworks and is often recommended for beginners. It was designed to clearly separate dosing days from observation days, making it easier to notice changes without overlap.

How the Fadiman protocol works

• Day 1: Microdose
• Day 2: No dose, observe lingering effects
• Day 3: No dose, return to baseline
• Day 4: Begin the cycle again

This pattern is typically followed for four to eight weeks, followed by a two to four week break. The simplicity of this structure makes it easier to track mood, focus, and energy shifts.

The Stamets stack protocol

The Stamets protocol introduces a more layered approach by combining psilocybin with additional supportive compounds. This method is often discussed by those interested in cognitive support and long-term brain health.

How the Stamets protocol works

• Days 1–4: Microdose combined with supportive supplements
• Days 5–7: No psilocybin

This weekly rhythm is commonly repeated for four weeks, followed by a multi-week break. Because it is more complex, it is generally recommended for those who already have experience with microdosing.

The two-days-a-week protocol

This protocol focuses on simplicity and flexibility. Instead of a repeating multi-day cycle, dosing occurs twice per week on non-consecutive days. This approach can work well for people with busy schedules who want a predictable rhythm.

Typical weekly structure

• One microdose early in the week
• One microdose later in the week
• At least one full day between doses

Cycles usually last four to eight weeks, followed by a rest period. Many people using this method choose consistent dosing formats such as microdose capsules to maintain accuracy.

Intuitive microdosing

Intuitive microdosing removes rigid schedules and instead relies on self-awareness. The main guideline is to avoid dosing on consecutive days, allowing space to integrate and reflect.

This approach is often adopted after completing one or more structured protocols. Experience helps individuals recognize when a microdose feels supportive and when rest is more beneficial.

Creating a personalized protocol